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Astex
Astex Therapeutics was a biotechnology company focused on the discovery and development of drugs in oncology and other areas. Astex was founded in 1999 by Sir Tom Blundell,〔(Tom Blundell: Director ) on OpenCorporates〕 Chris Abell & Harren Jhoti, and is located in Cambridge, England.
The company's research efforts focus on utilization of a proprietary "drug discovery engine" dubbed Pyramid. Astex has also solved the structure of two key cytochrome P450 isoenzymes involved in drug metabolism, 2C9 & 3A4, which the company hopes will help in optimizing the pharmacokinetic properties and safety of their lead compounds.
Astex Therapeutic's first drug candidate, a cell cycle inhibitor, entered Phase I clinical trials in 2005. Since that time they have created eight drugs that have progressed into the clinical stage of development.
==Recent news==
In September 2013, Astex was acquired by Otsuka Pharmaceutical for around $900 million.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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